Methyl salicylate
Salonpas (methyl salicylate) is a small molecule pharmaceutical. Methyl salicylate was first approved as Salonpas on 2008-02-20. It is used to treat acute pain, arthritis, back pain, contusions, and inflammation amongst others in the USA. It is known to target transient receptor potential cation channel subfamily A member 1.
Download report
Favorite
Events Timeline
Commercial
Clinical
Drug
Target
Variants
Financial
Trends
Safety
Events Timeline
5D
1M
3M
6M
YTD
1Y
2Y
5Y
Max
Events
FDA approval date
EMA approval date
Patent expiration date
Study first post date
Last update post date
Start date
Primary completion date
Completion date
Results first post date
Mock data
Subscribe for the real data
Subscribe for the real data
Commercial
Therapeutic Areas
Trade Name
FDA
EMA
Combinations
Salonpas
Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
Menthol
+
Methyl salicylate
Tradename | Company | Number | Date | Products |
|---|---|---|---|---|
| SALONPAS | Hisamitsu Pharmaceutical | N-022029 OTC | 2008-02-20 | 2 products, RLD, RS |
Labels
FDA
EMA
Brand Name | Status | Last Update |
|---|---|---|
| 10% methyl salicylate pain relief patch | C200263 | 2024-06-27 |
| 1st medxpatch | C200263 | 2024-10-31 |
| 365 whole foods market anticavity/antigingivitis mouthwash | OTC monograph not final | 2022-05-12 |
| 701 dieda zhengtong yaogao medicated | OTC monograph not final | 2019-11-13 |
| 701 dieda zhengtong yaogao medicated plaster | OTC monograph not final | 2014-06-26 |
| advanced antiseptic citrus | OTC monograph not final | 2012-04-02 |
| advanced citrus antiseptic | OTC monograph not final | 2012-03-26 |
| advil targeted relief | C200263 | 2024-02-08 |
| ageless pain relief | C200263 | 2023-12-12 |
| air sinsin pas | OTC monograph final | 2011-06-06 |
Show 564 more
Agency Specific
FDA
EMA
No data
ATC Codes
No data
HCPCS
No data
Clinical
Clinical Trials
422 clinical trials
View more details
Mock data
Subscribe for the real data
Subscribe for the real data
Indications Phases 4
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Pain | D010146 | EFO_0003843 | R52 | 12 | 11 | 13 | 2 | 18 | 54 |
| Neuralgia | D009437 | EFO_0009430 | — | 3 | 11 | 8 | 6 | 13 | 39 |
| Healthy volunteers/patients | — | — | — | 12 | 3 | — | 1 | 10 | 25 |
| Cough | D003371 | — | R05 | 7 | 5 | — | 2 | 13 | 25 |
| Knee osteoarthritis | D020370 | EFO_0004616 | M17 | 3 | 2 | 5 | 2 | 6 | 18 |
| Osteoarthritis | D010003 | EFO_0002506 | M15-M19 | 2 | 1 | 5 | 3 | 6 | 17 |
| Postherpetic neuralgia | D051474 | — | — | 1 | 6 | 5 | 3 | 2 | 15 |
| Syndrome | D013577 | — | — | 2 | 2 | — | 2 | 7 | 12 |
| Rhinitis | D012220 | EFO_0008521 | J31 | 1 | 3 | 1 | 4 | 3 | 12 |
| Diabetic neuropathies | D003929 | EFO_1000783 | — | — | 4 | 6 | 2 | 2 | 12 |
Show 35 more
Indications Phases 3
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Peripheral nervous system diseases | D010523 | — | G64 | 1 | 7 | 12 | — | 7 | 25 |
| Back pain | D001416 | — | M54 | — | — | 2 | — | 11 | 13 |
| Low back pain | D017116 | — | M54.5 | — | — | 2 | — | 10 | 12 |
| Nervous system diseases | D009422 | — | G00-G99 | — | 5 | 7 | — | 1 | 12 |
| Breast neoplasms | D001943 | EFO_0003869 | C50 | 1 | 3 | 1 | — | 4 | 9 |
| Herpes zoster | D006562 | EFO_0006510 | B02 | — | 5 | 4 | — | — | 8 |
| Acute pain | D059787 | — | R52 | 1 | 1 | 2 | — | 4 | 7 |
| Neck pain | D019547 | — | M54.2 | — | 1 | 1 | — | 5 | 7 |
| Hiv infections | D015658 | EFO_0000764 | B20 | — | 4 | 3 | — | — | 7 |
| Capsicum | D002212 | — | — | — | — | 1 | — | 4 | 5 |
Show 21 more
Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Deglutition disorders | D003680 | — | R13.1 | — | 2 | — | — | 8 | 10 |
| Stroke | D020521 | EFO_0000712 | I63.9 | 2 | 3 | — | — | 4 | 8 |
| Pruritus | D011537 | — | L29 | 1 | 1 | — | — | 4 | 5 |
| Myofascial pain syndromes | D009209 | EFO_1001054 | — | — | 1 | — | — | 4 | 5 |
| Fibromyalgia | D005356 | EFO_0005687 | M79.1 | — | 1 | — | — | 4 | 5 |
| Postoperative pain | D010149 | — | G89.18 | — | 2 | — | — | 3 | 5 |
| Carcinoma | D002277 | — | C80.0 | 2 | 2 | — | — | — | 3 |
| Hypertension | D006973 | EFO_0000537 | I10 | — | 2 | — | — | 1 | 3 |
| Pulmonary hypertension | D006976 | EFO_0001361 | I27.20 | — | 2 | — | — | 1 | 3 |
| Parkinson disease | D010300 | EFO_0002508 | G20 | 2 | 1 | — | — | 1 | 3 |
Show 50 more
Indications Phases 1
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Chronic cough | D000096822 | — | R05.3 | 1 | — | — | — | 9 | 10 |
| Headache | D006261 | — | R51 | 2 | — | — | — | 3 | 5 |
| Migraine disorders | D008881 | EFO_0003821 | G43 | 2 | — | — | — | 2 | 4 |
| Chronic obstructive pulmonary disease | D029424 | EFO_0000341 | J44.9 | 2 | — | — | — | 2 | 4 |
| Tobacco use disorder | D014029 | — | F17 | 3 | — | — | — | 1 | 4 |
| Smoking | D012907 | EFO_0004318 | — | 3 | — | — | — | 1 | 4 |
| Amyotrophic lateral sclerosis | D000690 | EFO_0000253 | G12.21 | 2 | — | — | — | 1 | 3 |
| Motor neuron disease | D016472 | EFO_0003782 | G12.2 | 2 | — | — | — | 1 | 3 |
| Wounds and injuries | D014947 | — | T14.8 | 1 | — | — | — | 2 | 3 |
| Obstructive lung diseases | D008173 | — | — | 1 | — | — | — | 2 | 3 |
Show 53 more
Indications Without Phase
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Asthma | D001249 | EFO_0000270 | J45 | — | — | — | — | 6 | 6 |
| Hypotrichosis | D007039 | — | — | — | — | — | — | 4 | 4 |
| Prostatic hyperplasia | D011470 | EFO_0000284 | N40 | — | — | — | — | 4 | 4 |
| Hyperplasia | D006965 | EFO_0000536 | — | — | — | — | — | 4 | 4 |
| Radiculopathy | D011843 | — | M54.1 | — | — | — | — | 3 | 3 |
| Periodontitis | D010518 | EFO_0000649 | K05.3 | — | — | — | — | 3 | 3 |
| Atrial fibrillation | D001281 | EFO_0000275 | I48.0 | — | — | — | — | 3 | 3 |
| Physical therapy modalities | D026741 | — | — | — | — | — | — | 2 | 2 |
| Gastroesophageal reflux | D005764 | EFO_0003948 | K21 | — | — | — | — | 2 | 2 |
| Metabolism | D008660 | GO_0008152 | — | — | — | — | — | 2 | 2 |
Show 143 more
Epidemiology
Epidemiological information for investigational and approved indications
View more details
Drug
General
| Drug common name | Methyl salicylate |
| INN | — |
| Description | Methyl salicylate is a benzoate ester that is the methyl ester of salicylic acid. It has a role as a flavouring agent, a metabolite and an insect attractant. It is a benzoate ester, a member of salicylates and a methyl ester. It is functionally related to a salicylic acid. |
| Classification | Small molecule |
| Drug class | anti-inflammatory agents (salicylic acid derivatives) |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | COC(=O)c1ccccc1O |
Identifiers
| PDB | — |
| CAS-ID | 119-36-8 |
| RxCUI | — |
| ChEMBL ID | CHEMBL108545 |
| ChEBI ID | 31832 |
| PubChem CID | 4133 |
| DrugBank | — |
| UNII ID | — |
Target
Agency Approved
No data
Alternate
TRPA1
TRPA1
Organism
Homo sapiens
Gene name
TRPA1
Gene synonyms
ANKTM1
NCBI Gene ID
Protein name
transient receptor potential cation channel subfamily A member 1
Protein synonyms
ankyrin-like with transmembrane domains 1, Ankyrin-like with transmembrane domains protein 1, p120, Transformation-sensitive protein p120, Wasabi receptor
Uniprot ID
Mouse ortholog
Trpa1 (277328)
transient receptor potential cation channel subfamily A member 1 (Q8BLA8)
Variants
No data
Financial
Revenue by drug
$
€
£
₣
No data
Estimated US medical usage
Methyl salicylate
+
Menthol
Total medical expenditures per year (USD, in millions)
Mock data
Subscribe for the real data
Subscribe for the real data
Number of persons purchased
Mock data
Subscribe for the real data
Subscribe for the real data
Number of purchases
Mock data
Subscribe for the real data
Subscribe for the real data
Refill frequency
Mock data
Subscribe for the real data
Subscribe for the real data
Price per prescription (USD)
Mock data
Subscribe for the real data
Subscribe for the real data
Methyl salicylate
Total medical expenditures per year (USD, in millions)
Mock data
Subscribe for the real data
Subscribe for the real data
Number of persons purchased
Mock data
Subscribe for the real data
Subscribe for the real data
Number of purchases
Mock data
Subscribe for the real data
Subscribe for the real data
Refill frequency
Mock data
Subscribe for the real data
Subscribe for the real data
Price per prescription (USD)
Mock data
Subscribe for the real data
Subscribe for the real data
Tabular view
Trends
PubMed Central
Top Terms for Disease or Syndrome:
Mock data
Subscribe for the real data
Subscribe for the real data
Additional graphs summarizing 10,107 documents
View more details
Safety
Black-box Warning
Black-box warning for: Caplyta, Diclovix, Diclovix m, Fenovar, Lumason, Varophen
Adverse Events
Top Adverse Reactions
Mock data
Subscribe for the real data
Subscribe for the real data
420,992 adverse events reported
View more details
© 2020-2025 Collaborative Drug Discovery Inc. (CDD) | Terms of Use