Methyl salicylate
Salonpas (methyl salicylate) is a small molecule pharmaceutical. Methyl salicylate was first approved as Salonpas on 2008-02-20. It is used to treat acute pain, arthritis, back pain, contusions, and inflammation amongst others in the USA. It is known to target transient receptor potential cation channel subfamily A member 1.
Download report
Favorite
Events Timeline
Commercial
Clinical
Drug
Target
Variants
Financial
Trends
Safety
Events Timeline
5D
1M
3M
6M
YTD
1Y
2Y
5Y
Max
Events
FDA approval date
EMA approval date
Patent expiration date
Study first post date
Last update post date
Start date
Primary completion date
Completion date
Results first post date
Mock data
Subscribe for the real data
Subscribe for the real data
Commercial
Therapeutic Areas
Trade Name
FDA
EMA
Combinations
Salonpas
Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
Menthol
+
Methyl salicylate
Tradename | Company | Number | Date | Products |
|---|---|---|---|---|
| SALONPAS | Hisamitsu Pharmaceutical | N-022029 OTC | 2008-02-20 | 2 products, RLD, RS |
Labels
FDA
EMA
Brand Name | Status | Last Update |
|---|---|---|
| 10% methyl salicylate pain relief patch | C200263 | 2024-06-27 |
| 1st medxpatch | unapproved drug other | 2026-08-11 |
| 365 whole foods market anticavity/antigingivitis mouthwash | OTC monograph not final | 2022-05-12 |
| 5kind dmso | C200263 | 2025-12-02 |
| 701 dieda zhengtong yaogao medicated | OTC monograph not final | 2019-11-13 |
| 701 dieda zhengtong yaogao medicated plaster | OTC monograph not final | 2014-06-26 |
| abejas y viboras roll on | C200263 | 2025-07-22 |
| advanced antiseptic citrus | C200263 | 2025-02-20 |
| advanced citrus antiseptic | C200263 | 2025-01-10 |
| advil targeted relief | C200263 | 2024-02-08 |
Show 602 more
Indications
FDA
EMA
Agency Specific
FDA
EMA
No data
ATC Codes
No data
HCPCS
No data
Clinical
Clinical Trials
483 clinical trials
View more details
Mock data
Subscribe for the real data
Subscribe for the real data
Indications Phases 4
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Pain | D010146 | EFO_0003843 | R52 | 14 | 11 | 12 | 2 | 26 | 63 |
| Neuralgia | D009437 | EFO_0009430 | — | 3 | 10 | 6 | 6 | 15 | 38 |
| Healthy volunteers/patients | — | — | — | 12 | 3 | — | 1 | 10 | 25 |
| Cough | D003371 | — | R05 | 7 | 5 | — | 2 | 13 | 25 |
| Knee osteoarthritis | D020370 | EFO_0004616 | M17 | 3 | 2 | 5 | 2 | 7 | 19 |
| Osteoarthritis | D010003 | EFO_0002506 | M15-M19 | 2 | 1 | 5 | 3 | 6 | 17 |
| Postherpetic neuralgia | D051474 | — | — | 1 | 6 | 5 | 3 | 3 | 16 |
| Diabetic neuropathies | D003929 | EFO_1000783 | — | 1 | 4 | 6 | 3 | 2 | 14 |
| Rhinitis | D012220 | EFO_0008521 | J31 | 1 | 2 | 1 | 4 | 3 | 11 |
| Herpes zoster | D006562 | EFO_0006510 | B02 | — | 5 | 4 | 1 | 1 | 10 |
Show 41 more
Indications Phases 3
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Peripheral nervous system diseases | D010523 | — | G64 | — | 7 | 10 | — | 5 | 20 |
| Nervous system diseases | D009422 | — | G00-G99 | — | 5 | 7 | — | 1 | 12 |
| Neck pain | D019547 | — | M54.2 | — | 1 | 1 | — | 10 | 12 |
| Breast neoplasms | D001943 | EFO_0003869 | C50 | 1 | 3 | 1 | — | 6 | 11 |
| Back pain | D001416 | — | M54 | — | — | 1 | — | 9 | 10 |
| Acute pain | D059787 | — | R52 | 2 | 1 | 2 | — | 5 | 9 |
| Motor activity | D009043 | EFO_0003940 | — | 1 | — | 1 | — | 6 | 8 |
| Hiv infections | D015658 | EFO_0000764 | B20 | — | 4 | 3 | — | — | 7 |
| Chronic pain | D059350 | — | — | — | — | 1 | — | 5 | 6 |
| Prostatic neoplasms | D011471 | — | C61 | 1 | 2 | 2 | — | — | 5 |
Show 21 more
Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Deglutition disorders | D003680 | — | R13.1 | — | 2 | — | — | 8 | 10 |
| Stroke | D020521 | EFO_0000712 | I63.9 | 2 | 3 | — | — | 5 | 9 |
| Myofascial pain syndromes | D009209 | EFO_1001054 | — | — | 1 | — | — | 6 | 7 |
| Fibromyalgia | D005356 | EFO_0005687 | M79.1 | — | 1 | — | — | 6 | 7 |
| Pruritus | D011537 | — | L29 | 1 | 1 | — | — | 5 | 6 |
| Postoperative pain | D010149 | — | G89.18 | — | 2 | — | — | 3 | 5 |
| Intervertebral disc displacement | D007405 | EFO_1001800 | — | 1 | 1 | — | — | 4 | 5 |
| Hypertension | D006973 | EFO_0000537 | I10 | — | 2 | — | — | 2 | 4 |
| Type 2 diabetes mellitus | D003924 | EFO_0001360 | E11 | — | 1 | — | — | 3 | 4 |
| Pulmonary hypertension | D006976 | EFO_0001361 | I27.20 | — | 2 | — | — | 1 | 3 |
Show 49 more
Indications Phases 1
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Chronic cough | D000096822 | — | R05.3 | 3 | — | — | — | 9 | 12 |
| Smoking | D012907 | EFO_0004318 | — | 3 | — | — | — | 3 | 6 |
| Headache | D006261 | — | R51 | 1 | — | — | — | 4 | 5 |
| Chronic obstructive pulmonary disease | D029424 | EFO_0000341 | J44.9 | 2 | — | — | — | 2 | 4 |
| Tobacco use disorder | D014029 | — | F17 | 3 | — | — | — | 1 | 4 |
| Amyotrophic lateral sclerosis | D000690 | EFO_0000253 | G12.21 | 2 | — | — | — | 1 | 3 |
| Motor neuron disease | D016472 | EFO_0003782 | G12.2 | 2 | — | — | — | 1 | 3 |
| Obstructive lung diseases | D008173 | — | — | 1 | — | — | — | 2 | 3 |
| Aging | D000375 | GO_0007568 | R41.81 | 1 | — | — | — | 2 | 3 |
| Neoplasm metastasis | D009362 | EFO_0009708 | — | 2 | — | — | — | — | 2 |
Show 46 more
Indications Without Phase
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Low back pain | D017116 | — | M54.5 | — | — | — | — | 13 | 13 |
| Asthma | D001249 | EFO_0000270 | J45 | — | — | — | — | 6 | 6 |
| Hypotrichosis | D007039 | — | — | — | — | — | — | 4 | 4 |
| Prostatic hyperplasia | D011470 | EFO_0000284 | N40 | — | — | — | — | 4 | 4 |
| Hyperplasia | D006965 | EFO_0000536 | — | — | — | — | — | 4 | 4 |
| Periodontitis | D010518 | EFO_0000649 | K05.3 | — | — | — | — | 4 | 4 |
| Tobacco use | D064424 | — | Z72.0 | — | — | — | — | 4 | 4 |
| Radiculopathy | D011843 | — | M54.1 | — | — | — | — | 3 | 3 |
| Burns | D002056 | — | T30.0 | — | — | — | — | 3 | 3 |
| Kinesiophobia | D000092442 | — | — | — | — | — | — | 3 | 3 |
Show 170 more
Epidemiology
Epidemiological information for investigational and approved indications
View more details
Drug
General
| Drug common name | Methyl salicylate |
| INN | — |
| Description | Methyl salicylate is a benzoate ester that is the methyl ester of salicylic acid. It has a role as a flavouring agent, a metabolite and an insect attractant. It is a benzoate ester, a member of salicylates and a methyl ester. It is functionally related to a salicylic acid. |
| Classification | Small molecule |
| Drug class | anti-inflammatory agents (salicylic acid derivatives) |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | COC(=O)c1ccccc1O |
Identifiers
| PDB | — |
| CAS-ID | 119-36-8 |
| RxCUI | — |
| ChEMBL ID | CHEMBL108545 |
| ChEBI ID | 31832 |
| PubChem CID | 4133 |
| DrugBank | — |
| UNII ID | — |
Target
Agency Approved
No data
Alternate
TRPA1
TRPA1
Organism
Homo sapiens
Gene name
TRPA1
Gene synonyms
ANKTM1
NCBI Gene ID
Protein name
transient receptor potential cation channel subfamily A member 1
Protein synonyms
ankyrin-like with transmembrane domains 1, Ankyrin-like with transmembrane domains protein 1, p120, Transformation-sensitive protein p120, Wasabi receptor
Uniprot ID
Mouse ortholog
Trpa1 (277328)
transient receptor potential cation channel subfamily A member 1 (Q8BLA8)
Variants
No data
Financial
Revenue by drug
$
€
£
â‚£
Oxlumo – Alnylam Pharmaceuticals
Mock data
Subscribe for the real data
Subscribe for the real data
Mock data
Subscribe for the real data
Subscribe for the real data
Orkambi – Vertex Pharmaceuticals
Mock data
Subscribe for the real data
Subscribe for the real data
Mock data
Subscribe for the real data
Subscribe for the real data
Tabular view
Estimated US medical usage
Methyl salicylate
+
Menthol
Total medical expenditures per year (USD, in millions)
Mock data
Subscribe for the real data
Subscribe for the real data
Number of persons purchased
Mock data
Subscribe for the real data
Subscribe for the real data
Number of purchases
Mock data
Subscribe for the real data
Subscribe for the real data
Refill frequency
Mock data
Subscribe for the real data
Subscribe for the real data
Price per prescription (USD)
Mock data
Subscribe for the real data
Subscribe for the real data
Methyl salicylate
Total medical expenditures per year (USD, in millions)
Mock data
Subscribe for the real data
Subscribe for the real data
Number of persons purchased
Mock data
Subscribe for the real data
Subscribe for the real data
Number of purchases
Mock data
Subscribe for the real data
Subscribe for the real data
Refill frequency
Mock data
Subscribe for the real data
Subscribe for the real data
Price per prescription (USD)
Mock data
Subscribe for the real data
Subscribe for the real data
Tabular view
Trends
PubMed Central
Top Terms for Disease or Syndrome:
Mock data
Subscribe for the real data
Subscribe for the real data
Additional graphs summarizing 9,999 documents
View more details
Safety
Black-box Warning
Black-box warning for: Caplyta, Diclovix m, Fenovar, Lumason, Orthaphen, Orthrexo, Torvex, Varophen
Adverse Events
Top Adverse Reactions
Mock data
Subscribe for the real data
Subscribe for the real data
707,803 adverse events reported
View more details
© 2020-2025 Collaborative Drug Discovery Inc. (CDD) | Terms of Use